Zycortal® Suspension (desoxycorticosterone pivalate injectable suspension)

For use in: Dogs only

Zycortal Suspension contains desoxycorticosterone pivalate which is a mineralocorticoid hormone indicated for use as replacement therapy for mineralocorticoid deficiency in dogs with primary hypoadrenocorticism (Addison’s disease). Zycortal Suspension was formulated and approved specifically for subcutaneous use.

The desoxycorticosterone pivalate (DOCP) in Zycortal Suspension is a pure mineralocorticoid hormone that regulates electrolytes and water balance, which are impaired in cases of mineralocorticoid deficiency in Addison’s disease. DOCP has limited glucocorticoid activity, allowing the independent dose titration of mineralocorticoid without the risk of inducing marked side effects from glucocorticoid oversupplementation e.g. polyuria, polydipsia, polyphagia and muscle atrophy.

Zycortal Suspension should be used with caution in dogs with congestive heart disease, edema, severe renal disease or primary hepatic failure.

Zycortal Suspension allows you to tailor the dose of mineralocorticoid replacement and the concurrently administered glucocorticoid replacement therapy to the individual dog based on clinical response and normalization of Na+ and K+ concentrations

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